Journal of Proteomics & Bioinformatics
Open Access
ISSN: 0974-276X
ISSN: 0974-276X
Sameh Magdeldin
Institute of Nephrology,
Graduate School of Medical and Dental Sciences, Niigata University
Japan
Short Article
“All and None”
Refining Strategy; Fishing Your Correct Protein from
Proteomics Ocean
Author(s): Sameh Magdeldin, Yutaka Yoshida, Ying Zhang, Bo Xu, Eishin Yaoita and Tadashi YamamotoSameh Magdeldin, Yutaka Yoshida, Ying Zhang, Bo Xu, Eishin Yaoita and Tadashi Yamamoto
We have developed an easy-to use methodology for refining large extensible markup language (XML) - based proteomics dataset with a high stringent and simple approach using VBA- coded plug-in. A methodology we term it (All and None). Selections of targeted candidates differentially significant between compared groups were selected based on its appearance or absence followed by peptide screening with a novel and simple approach. By testing the reliability and efficiency of this method, All and None was confirmed to be an applicable process for initial screening of biological biomarkers in complex specimens and tissue extract... View More»
DOI:
10.4172/jpb.1000178