Reproductive System & Sexual Disorders: Current Research
Open Access

Samuel Onuoha

Publications

• Research Article
  Effect of Ethanolic Extract of Cannabis sativa on Progesterone and Estrogen Hormones in Female Wistar Rats
  Author(s): Chioma Okereke and Samuel Onuoha Chioma Okereke and Samuel Onuoha
  
  Cannabis sativa have been suggested to disrupt the normal ovulatory cycle and hormonal secretion in animals. In this study, we investigated the changes in progesterone and estrogen levels in female Wistar rats as a result of oral administration of ethanolic extract of C. sativa for 7, 14 and 21 days consecutively. A total of 18 female rats were used and selectively divided into three groups (A, B and C) based on their body weight. Group A was control group while Group B and C were test groups and were given 200 ml and 400 ml/kg body weight of the extract respectively. At the end of each week, blood sample was collected from the various groups and subjected to estrogen and progesterone hormonal assay. The estrogen levels observed in Groups B and C were 6.33 ± 5.30 and 2.23 ± 1.07 respectively after 21 days. At th.. View More»
  DOI: 10.4172/2161-038X.1000150

  Abstract PDF

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