Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
Open Access

Sandler B

Publications

• Research Article
  Profound Pituitary Suppression Following Oral Contraceptive Pretreatment in Gonadotropin-releasing Hormone Antagonist Cycles Does Not Impact Outcome: A Retrospective Cohort Study
  Author(s): Vela G*, Ruman J, Luna M, Sandler B, and Coppermana ABVela G*, Ruman J, Luna M, Sandler B, and Coppermana AB
  
  Background: This retrospective study evaluated the effect of profound pituitary suppression with oral contraceptive pill (OCP) pretreatment in gonadotropin-releasing hormone (GnRH) antagonist cycles stimulated with recombinant follicle stimulating hormone plus highly purified human menopausal gonadotropin. Methods: The analysis included women aged 20-46 years (N=318) who utilized OCP pretreatment in a private academic in vitro fertilization center between January 2008 and January 2010. Patients were retrospectively divided based on endogenous luteinizing hormone (LH) level (≤ 1.5 [n=75] vs. >1.5 [n=243] mI U/mL) on stimulation day 1. Results: In the LH ≤ 1.5 and >1.5 mIU/mL groups, respectively, the mean number of stimulation days was 10.9 and 9.5 days (P<0.0001); mean total gonadotropin use was 4,328 and 3,543 IU (P<0.0001). Oocyte retrieval was greater in the.. View More»
  DOI: 10.4172/2375-4508.1000200

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