Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Sandro Matas
Brazil
Case Report
Pseudotumor Cerebri Associated with Leuprolide Acetate for Central Precocious Puberty-Case Report
Author(s): Renato Antunes Schiave Germano, Ruth Rocha Franco, Sandro Matas and Frederico Castelo MouraRenato Antunes Schiave Germano, Ruth Rocha Franco, Sandro Matas and Frederico Castelo Moura
This article represents the fourth case in literature of an association between pseudotumor cerebri (PTC) and leuprolide acetate, the first with precocious puberty and severe visual loss. A 9-year-old girl with precocious puberty was treated with a once-monthly dose of leuprolide acetate (3.75 mg) for three months. In the 4th month of treatment, it was decided to increase the dosage of leuprolide acetate to 11.25 mg in once-quarterly doses. After 1 month, she complained of holocranial headache, transient visual obscuration followed by progressive visual loss. After 6 months, she persisted with holocranial headache and progressive visual loss associated with ocular deviation. Neuro-opthalmological examination revealed severe visual loss and bilateral papilledema. Cerebrospinal fluid (CSF) analysis showed opening pressure of 45 cm H2O. The most likely diagnosis was PTC associated with l.. View More»
DOI:
10.4172/2155-9570.1000444