Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Saric O
Tanzania
Review Article
The Nature and Function of Immunogenic Tumor Proteins That Characterize Pancreatic and Colorectal Cancer: A Review
Author(s): Arlen M, Arlen P, Crawford J, Coppa G, Saric O, Bandovic J, Doubakovski A, Conte C, Wang X, Molmenti E and Hollinshead AArlen M, Arlen P, Crawford J, Coppa G, Saric O, Bandovic J, Doubakovski A, Conte C, Wang X, Molmenti E and Hollinshead A
The use of immunotherapy as it relates to the treatment of solid tumor malignancies appears to be an effective approach for managing many patients who present with both recurrent and metastatic disease. This holds true, especially in those cases where patients have failed current chemotherapeutic protocols and evidence of tumor progression is noted. In such instances, the delivery of the proper immunotherapeutic agents may be effective either alone or in combination with chemotherapy. The ideal approach would be in the identification of an immunogenic protein that characterized and was specific for the tumor system to be treated. One of the first attempts to utilize specific active immunotherapy for treating cancer patients with advanced disease was by Ariel Hollinshead. She produced several vaccine preparations composed of tumor associated antigen (TAA) derived from pooled allogeneic.. View More»
DOI:
10.4172/2155-9899.1000367