ISSN: 2155-6148
+44 1223 790975
Satoshi Hagiwara
Hasamamachi, Yufu City, Oita, 879-5593
Japan
Case Report
Sugammadex is Safe and Effective for Patients with Myasthenia Gravis
Author(s): Chihiro Shingu, Taichi Nishida, Satoshi Hagiwara, Keisuke Shiihara, Yoshimasa Oyama, Takakuni Abe and Takayuki NoguchiChihiro Shingu, Taichi Nishida, Satoshi Hagiwara, Keisuke Shiihara, Yoshimasa Oyama, Takakuni Abe and Takayuki Noguchi
Thymoma, which can be surgically treated under general anesthesia, is associated with the pathophysiology of myasthenia gravis. Muscle weakness is a hallmark of myasthenia gravis; therefore, these patients are hypersensitive to the effects of nondepolarizing muscle relaxants. Neuromuscular blockers can cause prolonged postoperative muscle relaxation, leading to decreased respiratory function. Therefore, careful administration of muscle relaxants during the perioperative period is important. The neuromuscular antagonist, sugammadex, has been used to counteract problems associated with muscle relaxants. By encapsulating nondepolarizing muscle relaxants, sugammadex can reverse the neuromuscular blockade. Here we report three cases of myasthenia gravis. In each case, perioperative management included use of a train-of-four (TOF) monitor to minimize muscle relaxant use during surgery. Suga.. View More»
DOI:
10.4172/2155-6148.1000122