Journal of Medical Diagnostic Methods
Open Access
ISSN: 2168-9784
+44 1300 500008
ISSN: 2168-9784
+44 1300 500008
Satoshi Sugawa
Abbott Japan Co, Ltd, Diagnostics Division,
3-5-27, Mita, Minato-ku, Tokyo, 108-6305
Japan
Research Article
Significance of Screening the General Population for Potential Cardiovascular Diseases with a Combination Assay of B-type Natriuretic Peptide and High Sensitive Troponin I
Author(s): Sugawa S
Sugawa S
Objectives: With increasing number of deaths by cardiovascular diseases, to develop an efficient method to screen the general population, such as a screening using biomarkers, for potential cardiovascular diseases is essential. We assessed the effectiveness of a combination assay of B-type natriuretic peptide (BNP) and cardiac troponin I (TnI) in detecting individuals with high cardiovascular risks.
Methods: BNP and TnI were determined using Abbott Architect immunoassays in 950 subjects who visited Takeda Hospital Medical Examination Center for the annual health check.
Results: The BNP level and TnI level were independently and positively associated with the Framingham Risk Score (FRS). The presence of hypertension, and CKD were positively, but that of dyslipidemia was negatively associated with the BNP level, whil.. View More»
DOI:
10.4172/2168-9784.1000240