Journal of Clinical & Experimental Dermatology Research
Open Access

Seneviratne JKK

Publications

• Research Article
  Superantigen Profile of Staphylococcus Aureus Isolates from Patients with Atopic Dermatitis in Sri Lanka
  Author(s): Gomes PLR, Gathsaurie Neelika Malavige, Fernando N, Mahendra MHR, Seneviratne JKK and Graham S Ogg Gomes PLR, Gathsaurie Neelika Malavige, Fernando N, Mahendra MHR, Seneviratne JKK and Graham S Ogg
  
  Background:Staphylococcus aureus colonizes most patients with atopic dermatitis. Staphylococcus aureus is able to produce staphylococcal enterotoxins, staphylococcal enterotoxin-like toxins and Toxic shock syndrome toxin – 1.The presence of superantigen encoding genes has been associated with atopic dermatitis in other cohorts. Aim: To determine the association of different Staphylococcal superantigens with clinical disease severity in a tropical disease setting in patients with atopic dermatitis. Methodology: Skin swabs collected from 100 patients with atopic dermatitis and 120 controls were cultured. Severity of atopic dermatitis was graded using the Nottingham Eczema Severity Score. Bacterial DNA was extracted and superantigen genes were detected by separate PCRs. Results:52/59 (.. View More»
  DOI: 10.4172/2155-9554.1000136

  Abstract PDF

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