Journal of Thyroid Disorders & Therapy
Open Access

Sergiy Dolomatov

Publications

• Research Article
  Experimental Investigation of Acute and Delayed Renal Effect of Exogenous Thyroxine
  Author(s): Sergiy Dolomatov, Radoslaw Muszkieta and Walery Zukow Sergiy Dolomatov, Radoslaw Muszkieta and Walery Zukow
  
  Introduction: Normally, thyroid hormones are important regulators of metabolic processes in mammals. Aim: To study the renal function of rats in a single dose of thyroxine, as well as analysis of remote renal effects of experimental hyperthyroidism. Materials and methods: The study used inbred male rats massing 200-250 g, the experimental hyperthyroidism caused a 10-day daily intragastric sodium salt of thyroxine, suspended in 1% of starch gel. Thyroxine produced by Berlin Chemie (Germany) was administered to 20 micrograms per 100 g of body mass. The function of the kidneys of rats were studied under conditions of induced diuresis induced by water stress, 24 h after the single purpose of thyroxine, 24 h after the completion of the 10-day administration of the hormone, as well as 14 days after completion of the 10-d.. View More»
  DOI: 10.4172/2167-7948.1000105

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