Mycobacterial Diseases
Open Access

Seyyed Reza Moaddab

Publications

• Research Article
  A Study of the Effectiveness of Two Common Fluoroquinolones on Mycobacterial Strains Isolated From Patients
  Author(s): Abdolnasser Rafi and Seyyed Reza MoaddabAbdolnasser Rafi and Seyyed Reza Moaddab
  
  Background and objectives: Investigation and study of second-line drugs effects on mycobacterial strains has been of great importance due to prevalence of drug resistance especially multi-drug resistance (MDR) in Mycobacterium tuberculosis (MTB) strains in the recent years. The objective of this research was to determine drug sensitivity of Mycobacterium tuberculosis and mycobacteria other than tubercle bacilli (MOTT) strains to the two common second-line anti-mycobacterial fluoroquinolones, i.e. ofloxacin (OFL) and ciprofloxacin (CIP). Materials and methods: In this study, the in-vitro activities of two drugs of OFL and CIP, considering the effects of first-line drugs (isoniazid, rifampin, streptomycin and ethambutol) were studied on 100 mycobacterial strains containing 90 MTB and 10 MOTT strains isolated from patients admitted to research ce.. View More»
  DOI: 10.4172/2161-1068.1000119

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