ISSN: 2167-7948
+44 1300 500008
SGA de Meer
England
Research Article
High Negative Predictive Value (NPV) Of Undetectable TSH Stimulated Tg For Disease Recurrence In Both Low And High Risk Differentiated Thyroid Cancer
Author(s): SGA de Meer, MR Vriens1, GD Valk, IHM Borel Rinkes and B de Keizer
SGA de Meer, MR Vriens1, GD Valk, IHM Borel Rinkes and B de Keizer
The extend, intensity and timing of the follow-up of differentiated thyroid cancer (DTC) patients remains unclear. Recent studies identified an undetectable TSH stimulated Tg measurement after one year as a prognostic factor for the risk of recurrence during further follow-up, thereby further dividing patients based on risk for recurrence. Because patients experience their disease on an emotional basis rather than related to actual disease severity, follow-up should be targeted to detect recurrence without ‘over-investigating’ patients. The aim of our study was to investigate the recurrence rate in high and low risk patients with DTC and the need for repeated (TSH stimulated) Tg measurement. Methods: We retrospectively reviewed the medical records of 264 DTC patients with absent Tg-Ab and identified the patients with persistent/ recurrent disease. We compared recurrence ra.. View More»
DOI:
10.4172/2167-7948.1000149