Medicinal & Aromatic Plants
Open Access
ISSN: 2167-0412
+44 1300 500008
ISSN: 2167-0412
+44 1300 500008
Sheriff MM
Egypt
Research Article
Evaluation of Antimicrobial, Cytotoxic and Larvicidal Activity of
Zygophyllum Coccineum North Sinai, Egypt
Author(s): Elbadry MA, Elaasser MM, Elshiekh HH and Sheriff MMElbadry MA, Elaasser MM, Elshiekh HH and Sheriff MM
The antimicrobial larvicidal and cytotoxic properties of Zygophillum coccinium collected from desert of north
Sinai, Egypt. Antimicrobial activity of Z. coccinium extracts showed that ethyl acetate extract was the most potent
antimicrobial effect on bacterial and fungal test organisms against P. aeruginosa with inhibition zone 20 mm and
F. moniliforme with inhibition zone 22 mm. Cytotoxic effect of Z. coccinium extracts indicated that acetone extract
showed maximum cytotoxic activity on HeLa cell line, whereas methanol extract showed maximum cytotoxic
activity on MCF-7 cell line with cell line viability 13.36 and 35.19%, whereas the results of IC50 in HeLa cell line
showed that the boiled water ethyl acetate extract had the most potent IC50 with 6.25 µg/ml. the results of IC50 in
MCF-7 cell line the petroleum ether extract had the most potent IC50 with 18.75 µg/ml. Ethyl acetate.. View More»
DOI:
10.4172/2167-0412.1000214