ISSN: 2155-9880
+44 1300 500008
Shinjyo Sonoda
Japan
Research Article
The Correlation between Post-Procedural Plasma Fractalkine and Lipid Plaque Volume in Target Lesion after Coronary Stent Implantation
Author(s): Seiya Tanaka, Yoshitaka Muraoka, Yuki Tsuda, Shinjyo Sonoda, Masahiro Okazaki and Yutaka OtsujiSeiya Tanaka, Yoshitaka Muraoka, Yuki Tsuda, Shinjyo Sonoda, Masahiro Okazaki and Yutaka Otsuji
Several reports suggest that fractalkine (FKN) and its cognate receptor, CX3CR1, play a role in atherogenesis. Recent data showed that plasma FKN is elevated in patients with unstable angina pectoris and is more elevated with patients with plaque rapture. We assessed the hypothesis that plasma FKN might be elevated after stentimplantation and related to the plaque-characteristics. First of all we tested the time course of plasma FKN level 30-min., 3-hour, 6-hour and 12-hour after coronary stenting. Their levels are elevated at 30 min. after percutaneous coronary intervention (PCI) and maintained the level until 12-hour after PCI. Then we examined the plasma levels of FKN, IL-8 and IL-6 in fifty consecutive patients before and 12-hour after coronary stenting following in integrated backscatterintravascular ultrasound (IB-IVUS) analysis. The plasma IL-8 did .. View More»
DOI:
10.4172/2155-9880.1000234