ISSN: 2329-6488
Shushpanova TV
Mental Health Research Institute, Siberian Branch of Russian Medical Science,
4 Aleutskaya Street, Tomsk 634014
Serbia
Research Article
Influence of Maternal Alcoholism on the Brain Benzodiazepine Receptor Development in Human Embryo and Fetus during Ontogeny
Author(s): Shushpanova TV
Shushpanova TV
Graphical Abstract: Influence of maternal alcoholism on the brain benzodiazepine receptor development in human’s embryo and fetus showed decreases their affinity and increases density as compensatory adaptation of the fetal nervous system to the effects of alcohol.
Abstract: Signaling mechanisms that are required for proper neuronal development and how these processes are impaired by ethanol resulting in harmful consequences to brain development are very important for our understanding. The aim of the present work was to study the development of synaptic Benzodiazepine Receptors (BzDR) (functionally associated with the brain GABAergic system) in the brains of embryos and fetuses aged 8-15 weeks obtained from alcoholic female patients.
Material and method: Abortive material (samples of brain tissue) was obtain.. View More»
DOI:
10.4172/2329-6488.1000176