Journal of Developing Drugs
Open Access

Shylajab MR

Publications

• Research Article
  6-Gingerol is the most Potent Anticancerous Compound in Ginger (Zingiber officinale Rosc.)
  Author(s): Kumara M, Shylajab MR, Nazeemc PA, Babu T Kumara M, Shylajab MR, Nazeemc PA, Babu T
  
  Cancer is one of the most deadly diseases in the world, which is caused due to uncontrolled growth of cells or malfunction of genes that control normal cell growth and division. Because of high death rate associated with cancer and because of serious side effects of chemotherapy and radiation therapy, many cancer patients seek alternative complementary methods of treatment. Ginger (Zingiber officinale Rosc.) is an important spice crop with immense medicinal properties and health beneficial effects. All the ginger ligands showed good interaction with the selected targets but based on ADME/Toxicity analysis 6-gingerol was superior with respect to absorption, solubility, and less neurotoxic effect as compared to other ginger ligands. 6-gingerol was also found cytotoxic to all the three cancer cells lines were studied. The cytotoxicity increased with increase in concentration of 6-gingero.. View More»
  DOI: 10.4172/2329-6631.1000167

  Abstract PDF

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