Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Sidra Anam
Pakistan
Review Article
Lactic Acid Bacteria as Vectors: A Novel Approach for Mucosal Vaccine Delivery
Author(s): Beenish Israr, Jaehan Kim, Sidra Anam and Faisal Rasheed Anjum
Beenish Israr, Jaehan Kim, Sidra Anam and Faisal Rasheed Anjum
Lactic Acid Bacteria (LAB) has been used in food industry due to its classification as food grade microorganism. It has been used for food production as well as preservation on large scale. It is also considered as promising bacterial strain due to its probiotic activity that confirms human health. Moreover, it also shows resistance regarding its survival in Gastrointestinal Tract (GIT). Therefore, use of LAB as delivery platform for drugs as well as production of recombinant protein is a challenging approach for researchers now a day. As, it not only reduces the production cost of drug, but also act as live vector to synthesize and deliver target or therapeutic protein of interest. Moreover, it is possible to produce different proteins from same bacteria simultaneously. Thus altogether, this approach has not only provided an alternative option for intravenous administration of recomb.. View More»
DOI:
10.4172/2155-9899.1000548