ISSN: 2167-0412
+44 1300 500008
Silva GH
Brazil
Research Article
A New Β-Triketone and Antinociceptive Effect from the Essential Oil of the Leaves of Calyptranthes restingae Sobral (Myrtaceae)
Author(s): Passos LO, Pina LTS, de Jesus AM, de Melo MS, Bispo RM, Alves PB, de Lima PCN, de Souza VRM, Silva GH, Júnior LJQ, Thomazzi SM, Martins LRR, Ferreira AG, de Souza AR, Machado SMF and Guimarães AG
Passos LO, Pina LTS, de Jesus AM, de Melo MS, Bispo RM, Alves PB, de Lima PCN, de Souza VRM, Silva GH, Júnior LJQ, Thomazzi SM, Martins LRR, Ferreira AG, de Souza AR, Machado SMF and Guimarães AG
Calyptranthes restingae Sobral, known as “murta”, is a species of the northeastern Brazilian used to treat fever, pain and inflammatory disorders. The essential oil from Calyptranthes restingae Sobral (Myrtaceae) collected in Sergipe, northeastern Brazil, was obtained through the hydrodistillation and its antinociceptive properties were evaluated. Chromatographic analysis revealed 14 components, but only five were identified, accounting for 98.50% of the oil: (E)-caryophyllene (2.40%), calyptrantone (81.03%), α-humulene (1.52%), β-selinene (8.54%), α-selinene (5.01%). The structure of the major compound, calyptrantone, was elucidated by 1H and 13C-NMR. This is the first time that a β-triketone has been identified in the essential oil of Calyptranthes genus and that calyptrantone has been reported as a natural product. This essential oil showed an anti.. View More»
DOI:
10.4172/2167-0412.1000249