Journal of Cell Science & Therapy
Open Access

Somaya Hosny

Publications

• Research Article
  The Antidiabetic Effect of Mesenchymal Stem Cells vs. Nigella sativa Oil on Streptozotocin Induced Type 1 Diabetic Rats
  Author(s): Sally S Mohamed, Eman A I Ali and Somaya HosnySally S Mohamed, Eman A I Ali and Somaya Hosny
  
  Introduction: Diabetes is a chronic metabolic disorder that has no definitive cure till present. Currently; regenerative medicine using Mesenchymal Stem Cells (MSCs) offers promising treatment. Meanwhile, Nigella Sativa Oil (NSO) shows effectiveness for medication of various illnesses. Objective: This study compares the antidiabetic effect of MSCs vs. NSO on streptozotocin induced type 1 diabetes (T1D) in rat model. Methods: Human cord blood samples were collected. Isolated mononuclear cells were cultured and incubated to isolate MSCs. For experimental animals; after induction of T1D using multiple low dose streptozotocin (MLD-STZ), diabetic rats were divided into 6 groups (n =10); diabetic group 1 and 2 (sacrificed 15 and 30 days post-induction, consequently), NSO treated groups 1 and 2 (received daily NSO I.P. injection, sacrificed 15 and 30 days postinduction, conse.. View More»
  DOI: 10.4172/2157-7013.1000226

  Abstract PDF

Relevant Topics