ISSN: 2155-9899
Stephanie M. Karst
1600 SW Archer Road, Gainesville, FL 32610
Tanzania
Review Article
The Role of Type I Interferon in Regulating Norovirus Infections
Author(s): Stephanie M. KarstStephanie M. Karst
Noroviruses are responsible for a large majority of non-bacterial gastroenteritis outbreaks worldwide. They are considered to be the leading cause of foodborne disease outbreaks and are classified as category B biodefense agents. Noroviruses pose huge medical and economic burdens to the global community: While they display a rapid course of infection in healthy adults, several risk groups including children, the elderly, and immunocompromised individuals are susceptible to more severe and prolonged infections. Moreover, noroviruses can affect any semiclosed community including nursing homes, schools, disaster relief situations, vacation-based and military settings, and they are a major cause of hospital closures for the purpose of outbreak control. Elucidating the host immune responses contributing to the control of norovirus infections is essential to advance our understanding of nor.. View More»
DOI:
10.4172/2155-9899.S1-001