ISSN: 2329-6488
Stephen José Hanson
Tanzania
Research Article
Enhanced Cue Reactivity to Cocaine Cues in Non-treatment Seeking Cocaine Smokers
Author(s): Suchismita Ray, Catherine Hanson and Stephen Jose HansonSuchismita Ray, Catherine Hanson and Stephen Jose Hanson
Introduction: Cue reactivity is defined as an observable, classically conditioned response to drugs. Chronic cocaine use is associated with enhanced cue reactivity. Our aims were: (1) to evaluate reactivity to cocaine and neutral picture cues in non-treatment seeking chronic cocaine smokers who were abstinent from cocaine use for 72 hours and control participants using functional magnetic resonance imaging (fMRI), and (2) to assess whether cue reactivity related brain areas were correlated with subjective craving ratings.
Method: fMRI data were collected from non-treatment seeking cocaine-smokers (29-53 yrs.; 15M; 5F) who were abstinent from cocaine smoking for 72 hours, and control participants (25-53 yrs.; 13M; 4F) using a Siemens 3T magnet while they took part in a cue viewing task that included cocaine and neutral cues. Participants also p.. View More»
DOI:
10.4172/2329-6488.1000169