ISSN: 2157-7013
+44 1300 500008
Stuart RK
Tanzania
Research Article
Progression of Nodular Lymphocyte-Predominant Hodgkin’s Lymphoma to a High-Grade Lymphoma
Author(s): Riley JM, Jenrette JM, Gordon L, Milligan L, Zauls AJ and Stuart RKRiley JM, Jenrette JM, Gordon L, Milligan L, Zauls AJ and Stuart RK
Nodular lymphocyte-predominant Hodgkin’s lymphoma (NLPHL) is a rare subtype of Hodgkin’s lymphoma characterized by a nodular proliferation of large neoplastic B cells that are CD15 and CD30 negative. Although this neoplasm develops slowly and has a favorable prognosis with Stage I or II disease, it has a high rate of recurrence and patients tend to have repeated relapses [1]. Increasingly, reports have shown that a small percentage of patients with NLPHL may transform to a more aggressive lymphoma concurrently or many years later. This case highlights a 58 year-old man who developed NLPHL at age 33 and progressed to a high-grade malignant lymphoma 25 years later. The purpose of this report is to share this patient’s unusual clinical course and provide a pertinent literature review of NLPHL... View More»
DOI:
10.4172/2157-7013.S2-001