Journal of Cell Science & Therapy
Open Access
ISSN: 2157-7013
+44 1300 500008
ISSN: 2157-7013
+44 1300 500008
Taohong Hu
The General Hospital of the PLA Rocket Force,
Beijing
China
Review Article
Into the Eyes of Bone Marrow-Derived Mesenchymal Stem Cells Therapy
for Myocardial Infarction and Other Diseases
Author(s): Ming Yang, Zheng Zhang and Taohong Hu
Ming Yang, Zheng Zhang and Taohong Hu
Applications of bone marrow-derived mesenchymal stem cells (BM-MSCs) have been documented for diseases occur in the sports system, the central nervous system, the cardiovascular system etc. However, poor viability of donor stem cells after transplantation limits their therapeutic efficiency. Although the autophagy theory has been reported, the underlying mechanisms are still poorly understood. Isolation and culture methods of mesenchymal stem cells are currently concentrate on four ways. Overall, BM-MSCs have both important research significance and clinical application value in cell replacement therapy, gene therapy and reconstruction of tissues as well as organs especially for myocardial infarction. In this article, we review the biological characteristics of BM-MSCs and its research progress especially in myocardial infarction.
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DOI:
10.4172/2157-7013.1000266