Journal of Thyroid Disorders & Therapy
Open Access

Taraschenko YM

Biography

Dr. Yuriy M. Taraschenko is a senior researcher in the Department of Endocrine Gland Surgery at the V.P. Komisarenko Institute of Endocrinology and Metabolism, part of the National Academy of Medical Sciences of Ukraine in Kyiv. His work primarily focuses on the molecular mechanisms underlying endocrine disorders, with a particular emphasis on thyroid cancer. In 2015, Dr. Taraschenko co-authored a study titled "The Expression and Activation of Extracellular Signal-Regulated Kinases 1/2 in Papillary Thyroid Carcinomas," published in the SM Journal of Endocrinology and Metabolism. This research investigated the role of ERK1/2 signaling pathways in the development and progression of papillary thyroid carcinoma, providing insights into potential therapeutic targets. In 2018, he contributed to the study "Main Prognostic Factors for Well-Differentiated Thyroid Cancer: Analysis of Combined Patients' Treatment Results During 20 Years After Surgery," published in the Journal of Thyroid Disorders & Therapy. This long-term analysis identified key prognostic factors influencing patient outcomes, aiding in the development of more effective treatment strategies for thyroid cancer. Dr. Taraschenko's recent work includes the 2021 publication "Activation of the PI3K/AKT/MTOR/p70S6K1 Signaling Cascade in Peripheral Blood Mononuclear Cells in Patients with Type 2 Diabetes," featured in the Ukrainian Biochemical Journal. This study explored the activation of specific signaling pathways in immune cells of diabetic patients, contributing to the understanding of the molecular mechanisms involved in type 2 diabetes. Through his extensive research, Dr. Taraschenko continues to advance the field of endocrinology, particularly in understanding the molecular basis of endocrine diseases, thereby contributing to the development of targeted therapies and improved patient outcomes.

Publications

• Research Article
  Main Prognostic Factors for Well Differentiated Thyroid Cancer: Analis of Combined Patients Treatment Results during 20 Years after Surgery
  Author(s): Guda BB, Kovalenko AE, Bolgov MY, Taraschenko YM and Mykhailenko NIGuda BB, Kovalenko AE, Bolgov MY, Taraschenko YM and Mykhailenko NI
  
  Background: In general, the prognosis in patients with well differentiated thyroid carcinoma (WDTC) is excellent. However, there are small cohorts of patients who experience a more aggressive form of disease which is often associated with certain poor prognostic factors. Identifying these patients at an early stage is imperative for guiding treatment decisions. The purpose of the work is to study the cumulative survival of patients with WDTC, depending on a number of clinical and biological characteristics of tumors. Methods: A retrospective cohort study of patients operated on WDTC in the period from 1995 to 2015 (5526 people). Each patient was analyzed according to age, gender, tumor size and characteristics of the TNM (7 editions), clinical stage, volume of surgery, number of points on the MACIS scale, risk group, number of courses of rad.. View More»
  DOI: 10.4172/2167-7948.1000228

  Abstract PDF

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