Journal of Clinical Toxicology
Open Access

Tawfik HM

Publications

• Research Article
  Study of the Role of N-Acetyl Cysteine in Phosphide Poisoning
  Author(s): Tawfik HMTawfik HM
  
  Compounds containing phosphide used as rodenticide are among most fatal poisonings encountered in Poisoning Control Center, Ain Shams University Hospitals (PCCA) Cairo, Egypt. Its toxicity is associated with challenging oxidative damaging effects that involve all tissue cells. Patients develop severe hypotension and metabolic acidosis. No available data about specific antidotes for these compounds, however we assume that antioxidants may play a beneficial role in improving intoxicated patient outcome. N-acetyl cysteine (NAC) is supposed to have a protective role. Objective: To evaluate the role of antioxidant N-acetyl cysteine (NAC) in improving outcome of phosphide intoxicated patients. Methods: The study is double blind randomized clinical trial, carried on patients presented to PCCA over 3 years period (2015-2017) with severe zinc a.. View More»
  

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