Journal of Developing Drugs
Open Access
ISSN: 2329-6631
+44 1478 350008
ISSN: 2329-6631
+44 1478 350008
Teshager Aklilu Yesuf
College of Medicine and Health Sciences,
P.O. Box 1145, Dessie
Ethiopia
Research Article
Prevalence and Clinical Significance of Potential Drug-Drug Interactions at Ayder Referral Hospital, Northern Ethiopia
Author(s): Teshager Aklilu Yesuf, Abebe Zeleke Belay, Eskinder Ayalew Sisay and Zigbey Brhane GebreamlakTeshager Aklilu Yesuf, Abebe Zeleke Belay, Eskinder Ayalew Sisay and Zigbey Brhane Gebreamlak
Introduction: Clinically significant drug-drug interactions reduce effectiveness of drugs or cause fatal adverse events. Although harmful drug interactions are preventable, clinicians’ recognition and detection of drug interactions is not optimal.
Objective: To assess prevalence, clinical significance and factors associated with potential drug-drug interactions at medical ward of Ayder Referral Hospital, Ethiopia. Methods: A cross-sectional study was conducted to determine potential drug-drug interactions. A total of 204 patients’ medical records were analyzed for drug-drug interaction using Micromedex drug interaction software. Data were analyzed using SPSS version 16.
Results: We identified 135 interacting-combinations in a total of 266 potential drug-drug interactions (pDDIs) with a mean of 1.3 pDDIs per.. View More»
DOI:
10.4172/2329-6631.1000179