Journal of Clinical and Cellular Immunology
Open Access

Thabet Y

Publications

• Research Article
  Systemic Lupus Erythematosus in Children: A Study about 37 Tunisian Cases
  Author(s): Thabet Y, Mankaï A, Achour A, Sakly W, Trabelsi A, Harbi A, Amri F, Sfar MT and Ghedira IThabet Y, Mankaï A, Achour A, Sakly W, Trabelsi A, Harbi A, Amri F, Sfar MT and Ghedira I
  
  Aim: To determine the clinical and serological characteristics in pediatric systemic lupus erythematosus (SLE). Patients and methods: This retrospective study included 37 patients with SLE. All patients fulfilled the ACR revised criteria for SLE and diagnosed between 1994 and 2009. Anti-nuclear antibodies were detected by indirect immunofluorescence (IIF) on liver rat sections. Anti-dsDNA, anti-Sm, anti-nucleosome, anti-SSA, anti-SSB and anti- RNP antibodies were detected by ELISA. Anti-dsDNA antibodies were detected also by IIF on Chrithidia luciliae. Results: The most common signs were anemia (86.5%), proteinuria (73%) and malar rash (67.6%). The frequency of arthritis and photosensitivity were 45.9% and 43.2% respectively. Leucopenia, thrombocytopenia and oral ulcer were present in 37.8%, 32.4% and 18.9% of cases re.. View More»
  DOI: 10.4172/2155-9899.1000192

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