Cell & Developmental Biology
Open Access

Thiago Henrique Ladeira do Carmo

Publications

• Review Article
  Cancer Metastasis
  Author(s): Carlos Augusto Gomes, Cleber Soares Junior, Juliana Almeida do Valle, Carolina Teixeira de Assis Lopes, Andressa Barra, Camila Couto Gomes, Thiago Henrique Ladeira do Carmo and Felipe Couto Gomes Carlos Augusto Gomes, Cleber Soares Junior, Juliana Almeida do Valle, Carolina Teixeira de Assis Lopes, Andressa Barra, Camila Couto Gomes, Thiago Henrique Ladeira do Carmo and Felipe Couto Gomes
  
  With the aging population and an increased incidence of neoplastic diseases, the study of the etiology of tumors and the mechanisms involved in the process of metastasis has increased significantly. Although there has been remarkable progress in this area and many proposed theories, several questions still remain. The factors associated with the emergence of the primary tumor and the mechanisms of metastasis are difficult to understand for many surgeons and clinicians because of the involvement of complex genetic, biochemical and molecular models. The tumor metastasis is responsible for approximately 90% of all cancer-related deaths. The cancer metastatic process occurs in a series of progressive steps, which called “metastatic cascade”. Its occurrence is a necessary break of the normal homeostatic mechanisms, leading to a rearrangement of the stromal tissue adjacent to th.. View More»
  DOI: 10.4172/2168-9296.1000106

  Abstract PDF

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