Angiology: Open Access

Angiology: Open Access
Open Access

ISSN: 2329-9495

+44 1478 350008

Tong He

Tong He

China

Publications
  • Research Article
    The Aortic Windkessel Property Adaptation in Whole-body Immersion Stressed Mice
    Author(s): Yang Wang, Annie Christel Bell, Han Wang, Boakye Kwabena, Shouyan Fan, Linghua Piao, Tong He, Zhibin Chen and Lingfeng GaoYang Wang, Annie Christel Bell, Han Wang, Boakye Kwabena, Shouyan Fan, Linghua Piao, Tong He, Zhibin Chen and Lingfeng Gao

    Objective: Immersion induced hydrostatic pressure on thoracic cavity and limbs is one kind of cardiac overload model in simulating microgravity. We evaluated immersion hemodynamic parameters, investigated in vitro stretching induced aortic intact wall windkessel adaptations in whole-body immersion mice.Method: Kunming mice were divided into immersion group (n=20) and control group (n=10) randomize. In immersion group, mice further divided into immersion group (n=10) and immersion with weight-bearing group (5% of body weight, n=10). The immersion kept 20 min/day in warm water and continues for 1 week. The hemodynamic parameters were collected by left carotid artery cannulation and analyzed by biological signal acquisition system. Calculi of percussion wave were calculated with integral mode to determ.. View More»
    DOI: 10.4172/2329-9495.1000222

    Abstract PDF

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