Journal of Proteomics & Bioinformatics
Open Access

Tran The Thanh

Publications

• Research Article
  Changes of Serum Glycoproteins in Lung Cancer Patients
  Author(s): Tran The Thanh, Nguyen Thi Minh Phuong, Nguyen Bich Nhi and Phan Van Chi Tran The Thanh, Nguyen Thi Minh Phuong, Nguyen Bich Nhi and Phan Van Chi
  
  Lung cancer (LC) is one of the leading causes of cancer deaths worldwide and approximately 3 million individuals die from this disease each year. Therefore, detecting LC at its early stages is very important to achieve decreased LC mortality. While gene expression profiling has been successfully used to classify various tumors and assess tumor stages, the gene-based prediction for LC is not yet entirely dependable. In serum, glycosylation is one of the most common post-translational modifications, and glycoproteins play a core role in a diversity of biological processes and pathogenesis. The development of an analytical approach for the study of variations of human serum glycoproteins has been limited by the structural heterogeneity of the post-translational modifications and the complexity of glycomics. Thus, in this report we presen.. View More»
  DOI: 10.4172/jpb.1000004

  Abstract PDF

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