Autism-Open Access
Open Access

Valérie Compan

Publications

• Review Article
  Serotonin 4 Receptors: A Cornerstone in Anorexia Nervosa?
  Author(s): Valérie CompanValérie Compan
  
  Adaptive decision-making to eat is crucial for survival but in anorexia nervosa, the brain persistently supports reduced food intake despite the physiological need to consume food. How the brain persists in reducing food intake sometimes even to the point of death despite the evolution of multiple mechanisms to ensure survival by governing adaptive eating behaviors remains mysterious. Food intake is a conserved behavioral trait between all species and involves numerous biological systems including the old phylogenetically serotonergic system. The present review focuses on anorexia and the implication of specific serotonin (5-HT, 5-hydroxytryptamine) receptors in food intake. In this context, we found that an early restrictive food intake due to stress, critically engages goaldirected (decision-making) systems upon the control of the serotonin 5-HT4 receptors, supporting that an early .. View More»
  DOI: 10.4172/2165-7890.1000207

  Abstract PDF

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