Journal of Leukemia
Open Access

Victoria M Chia

Publications

• Review Article
  Adverse Events in Adults with Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL): A Literature Review of Recent Clinical Trials
  Author(s): Horst-Dieter Hummel, Max S Topp, Ellen T Chang, Victoria M Chia, Michael A Kelsh, Martha L Doemland, Shilpa Alekar and Anthony S Stein Horst-Dieter Hummel, Max S Topp, Ellen T Chang, Victoria M Chia, Michael A Kelsh, Martha L Doemland, Shilpa Alekar and Anthony S Stein
  
  Background: With the introduction of new therapy options for adult patients with relapsed or refractory (R/R) acute lymphoblastic leukemia (ALL), a better understanding of existing toxicity profiles is needed. Methods: A systematic literature review was conducted to summarize the toxicity profiles in clinical trials using chemotherapeutic regimens, tyrosine kinase inhibitor (TKI)-based approaches in Philadelphia chromosome-positive (Ph+) and Philadelphia chromosome-negative (Ph-) R/R ALL, or other targeted therapies. Seventeen eligible articles were identified that reported toxicity profiles. We grouped adverse events into the following categories: hematological, infectious, gastrointestinal, cardiovascular/renal/hepatic, and neurological, stratified by treatment type. Treatment-relat.. View More»
  DOI: 10.4172/2329-6917.1000208

  Abstract PDF

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