Andrology-Open Access
Open Access

Vincenzo De Sanctis

Publications

• Mini Review
  Androgen Therapy in Adolescents: A Review
  Author(s): Ashraf T Soliman, Vincenzo De Sanctis and Mohamed YassinAshraf T Soliman, Vincenzo De Sanctis and Mohamed Yassin
  
  Constitutional Delay of Growth and Puberty (CDGP) and hypogonadism are the two most common indications for Testosterone (T) therapy in adolescents. CDGP is a transient state of hypogonadotropic hypogonadism associated with prolongation of childhood phase of growth, delayed skeletal maturation, delayed and attenuated pubertal growth spurt. In pre-pubertal male with CDGP, T therapy can be used to induce pubertal development, accelerate growth and relieve the psychosocial complaints. However, some issues in the management are still unresolved. These include type, optimal timing, dose and duration of sex steroid treatment and the possible use of adjunctive or alternate therapy. In adolescents with permanent hypogonadism T therapy is used to induce then maintain pubescent development. Testosterone therapy enables the patient to decrease mood disturbances, fatigue, impaired virilization and.. View More»
  DOI: 10.4172/2167-0250.1000124

  Abstract PDF

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