ISSN: 2155-6148
Wataru Sakai
Chuouku, Sapporo, Hokkaido
Japan
Research Article
Angiotensin II Receptor Blocker versus Angiotensin-Converting Enzyme Inhibitor for Postoperative Acute Kidney Injury after Cardiac Surgery
Author(s): Wataru Sakai*, Naoyuki Hirata and Michiaki Yamakage
Wataru Sakai*, Naoyuki Hirata and Michiaki Yamakage
Background and aims: Acute Kidney Injury (AKI) after cardiac surgery is a serious complication and a risk factor of postoperative mortality. It has been suggested that Angiotensin Ii Receptor Blockers (ARBs) and Angiotensin- Converting Enzymes (ACE-Is) might be able to reduce the incidence of postoperative AKI after cardiac surgery. However, it remains unknown as to which of these drugs are better for protecting the renal function after cardiac surgery. We hypothesized that each of the ARBs and ACE-Is were able to differentially affect the postoperative AKI after cardiac surgery due to their differential drug efficacies. Thus, this current study investigated the association between the ARBs or ACE-Is and the postoperative AKI after cardiac surgery.
Methods: This retrospective single-center observational study was conducted in a community hospit.. View More»
DOI:
10.4172/2155-6148.1000820