Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
William E. Smiddy
Tanzania
Review Article
Identifying Local Structural and Optical Derangement in the Neural Retina of Individuals with Type 1 Diabetes
Author(s): Delia DeBuc, Erika Tatrai, Lenke Laurik, Boglarka Eniko Varga, Veronika Olvedy, Aniko Somogyi, William E. Smiddy and Gabor Mark SomfaiDelia DeBuc, Erika Tatrai, Lenke Laurik, Boglarka Eniko Varga, Veronika Olvedy, Aniko Somogyi, William E. Smiddy and Gabor Mark Somfai
Background: To identify local structural and optical derangement in the neural retina of individuals with type 1 diabetes having early diabetic retinopathy (DR) and compare with healthy non-diabetic controls and type 1 diabetic individuals having no DR.Methods: Optical coherence tomography (TDOCT) examination was performed on a total of 74 healthy eyes, 38 eyes with type 1 diabetes mellitus (DM) with no retinopathy and 43 eyes with mild DR (MDR). A total of 6 intraretinal layers were segmented on OCT images. Thickness and reflectance-based measurements were extracted for each OCT scan using features measured locally for each intraretinal layer.Results: In the analysis where local measures were averaged in the separated macular regions outside the foveola, the mean thickness values of the outer segment of p.. View More»
DOI:
10.4172/2155-9570.1000289