Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
+44 1223 790975
ISSN: 2155-6148
+44 1223 790975
Research Article
A Study of the Efficacy of Cardiac Antidysrhythmic Drugs in Attenuating
Haemodynamic Responses to Laryngoscopy and Endotracheal Intubation
in the Black Population
Author(s): Sanjeev Singh, Edwin Ferguson Laing, William Kwame Boakye Ansah Owiredu, Arti Singh and Anbarasu Annamalai
Sanjeev Singh, Edwin Ferguson Laing, William Kwame Boakye Ansah Owiredu, Arti Singh and Anbarasu Annamalai
Background: Laryngeal, tracheal and bronchial receptors are stimulated by mechanical and chemical irritants during laryngoscopy and endotracheal intubation. That almost always triggers powerful cardiovascular responses. Various attempts have been made to attenuate these responses. The aim of this study was to compare the efficacy and safety of cardiac antidysrhythmic drugs lidocaine, diltiazem and esmolol in the attenuation of cardiovascular responses to endotracheal intubation in the Black normotensive population.
Patients and Methods: A randomized controlled trial was conducted in 160 adult patients of ASA physical status I or II undergoing various elective surgeries. The patients were randomly divided into four groups of 40 patients in each group - C, L, D, and E. Group - “C” received no drug (control) as placebo, group -&ldqu.. View More»
DOI:
10.4172/2155-6148.1000326