Journal of Alcoholism & Drug Dependence
Open Access
ISSN: 2329-6488
ISSN: 2329-6488
William P Milberg
Tanzania
Research Article
White Matter and Cognitive Changes in Veterans Diagnosed with Alcoholism and PTSD
Author(s): Arkadiy L Maksimovskiy, Regina E McGlinchey, Catherine B Fortier, David H Salat, William P Milberg and Marlene Oscar-Berman
Arkadiy L Maksimovskiy, Regina E McGlinchey, Catherine B Fortier, David H Salat, William P Milberg and Marlene Oscar-Berman
Alcoholism frequently occurs in returning U.S. Veterans, and is often comorbid with Post Traumatic Stress Disorder (PTSD). The goal of this study was to investigate the relationship between white matter changes and neuropsychological alterations in Operation Enduring Freedom, and/or Operation Iraqi Freedom (OEF/OIF) alcoholic Veterans with two primary aims: (1) to examine the relationship of alcoholism to brain structure and function while controlling for the potential effects of comorbid PTSD, and (2) to examine whether the effects of alcoholism are moderated by the quantity of lifetime alcohol consumption. Our sample consisted of 71 deployed OEF/OIF Veterans stratified into four groups: alcoholics without PTSD, alcoholics with PTSD, participants with PTSD without comorbid alcoholism, and control participants without alcoholism or PTSD. Participants were given an extensive neuropsych.. View More»
DOI:
10.4172/2329-6488.1000144