Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Wojciech Łabuś
Centre for Burns Treatment in Siemianowice Slaskie,
Siemianowice Slaskie
Poland
Review Article
Preparation of Amniotic Membrane and It’s Application in the Treatment of Skin Loss and Lyell's Syndrome (Toxic Epidermal Necrolysis): Current State and New Opportunities
Author(s): Agnieszka Klama-Baryła, Wojciech Łabuś, Diana Kitala, Małgorzata Kraut and Marek KaweckiAgnieszka Klama-Baryła, Wojciech Łabuś, Diana Kitala, Małgorzata Kraut and Marek Kawecki
Amniotic membrane is a good protection against bacterial infections, reduces losses of proteins, fluids and electrolytes, decreases pain from burns and accelerates healing. Due to its richness in nutrients and low immunogenicity, it is often used as a skin substitute. Human amnion may be prepared in tissue banks, as biostatic or biovital grafts. There are various methods of amniotic graft preparations developed to make them efficient in surgical treatment and prevent the risk of transmission of infectious diseases. This paper presents the current clinical application of human amnion in the treatment of skin losses, such as burns to the face and Lyell's syndrome (toxic epidermal necrolysis). It also describes new applications of fetal membranes for other diseases. Placental grafts are often an alternative therapy in the situations when standard treatment does not yield desirable ef.. View More»
DOI:
10.4172/2155-9554.1000422