Autism-Open Access
Open Access

Wu Zeyang

Publications

• Review Article
  Do the Stem Cells Really Work with Autism Spectrum Disorders Associated with Neuro-Immune Interaction?
  Author(s): Gao Shane, Wang Juan, Wu Zeyang,Yuan Ping, Gao Fengjuan, Zhou fei, Cao Limei, Chen Xu, Zhu Hongwen and Xu JunGao Shane, Wang Juan, Wu Zeyang,Yuan Ping, Gao Fengjuan, Zhou fei, Cao Limei, Chen Xu, Zhu Hongwen and Xu Jun
  
  Autism spectrum disorders (ASDs), namely neurodevelopmental disorders encompassing impairments in communication, social interactions and restricted stereotypical behaviors, induces a relatively high morbidity and mortality ratio (1/166) in modern children's life. One of the serious factors accounting for ASDs is the failure of the appropriate neuro-immune interaction. Although a relationship between altered immune responses and ASDs was firstly recognized nearly 40 years ago, only recently has new evidence started to shed light on the complex multifaceted communication between neuro-immune dysfunction and behavior in ASDs. Extensive alterations in immune function have now been described in both children and adults with ASDs, including ongoing inflammation in brain specimens, elevated pro-inflammatory cytokine profiles in the Cerebro-Spinal Fluid (CSF) and blood, increased presence of .. View More»
  DOI: 10.4172/2165-7890.1000151

  Abstract PDF

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