Andrology-Open Access
Open Access

Xiansheng Zhang

Publications

• Research Article
  Combination of Sertraline and Sildenafil versus Sertraline Monotherapy in the Treatment of Acquired Premature Ejaculation without Concomitant Diseases
  Author(s): Xiansheng Zhang, Dongdong Tang, Jiajia Yang, Kai Shi, Jingjing Gao, Zongyao Hao, Jun Zhou and Chaozhao Liang Xiansheng Zhang, Dongdong Tang, Jiajia Yang, Kai Shi, Jingjing Gao, Zongyao Hao, Jun Zhou and Chaozhao Liang
  
  Objective: To determine the efficacy and safety of sertraline monotherapy and combination therapy with sertraline and sildenafil in the treatment of APE without concomitant diseases. Methods: The study was conducted in 120 outpatients diagnosed with APE but without concomitant diseases. These patients were randomly divided into two groups: group A was treated with 50 mg sertraline daily; group B was treated with 50 mg sertraline daily and 50 mg sildenafil as needed. Assessment of the efficacy and safety of the two therapies was performed after 4 and 8 weeks. Patient or partner reports of Intravaginal Ejaculatory Latency Time (IELT), Premature Ejaculation Profile (PEP), Clinical Global Impression of Change (CGIC), and Treatment-Emergent Adverse Events (TEAEs) were assessed in this study. All the assessments were compared in the two groups after the treatment period. The effic.. View More»
  DOI: 10.4172/2167-0250.1000117

  Abstract PDF

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