Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
+44 1223 790975
ISSN: 2155-6148
+44 1223 790975
Yahia Mahmoud Mahmoud
Egypt
Research Article
Comparative Study between Three Solutions for Cardioplegia in Pediatric Cardiac Surgery: Histidine-Tryptophan-Ketoglutarate (HTK) Solution, Blood Cardioplegia and Crystalloid (St. Thomas) Cardioplegia
Author(s): Mostafa Mohammed Elhamamsy , Hoda Hafez Bahi Eldin , Yahia Mahmoud Mahmoud , Mohammed Ahmed Hamed and Rana Ahmed Abdel-GhaffarMostafa Mohammed Elhamamsy , Hoda Hafez Bahi Eldin , Yahia Mahmoud Mahmoud , Mohammed Ahmed Hamed and Rana Ahmed Abdel-Ghaffar
Background: Cardioplegia is the solution used to arrest and protect the heart during aortic cross-clamping. Crystalloid and blood cardioplegia are both widely used in clinical practice. Custodial-HTK solution is an intracellular cardioplegic solution containing histidine, tryptophan and ketoglutarate. Aim: we compared the myocardial protective effects of 3 types of cardioplegia solution: The histidine–tryptophan– ketoglutarate (HTK) solution, blood and St.Thomas cardioplegia in pediatric cardiac surgery. Settings and Design: This study design was a prospective randomized controlled double blinded clinical study. Patients and Methods: 60 children aged 3-10 yrs of either sex who underwent elective cardiac surgery for acyanotic heart diseases using cardiopulmonary bypass were randomly allocated to three grou.. View More»
DOI:
10.4172/2155-6148.1000818