ISSN: 2161-1025
Yang Liu
China
Case Report
A Case of Thrombophlebitis Caused by Carbamazepine
Author(s): Xiufeng Qi, Yan Xu, Li Yang, Wenjing Qi, Jingyi Liu, Yang Liu, Xinping Wang, Xuguang Gao and Xianzeng Liu
Xiufeng Qi, Yan Xu, Li Yang, Wenjing Qi, Jingyi Liu, Yang Liu, Xinping Wang, Xuguang Gao and Xianzeng Liu
Objective: To present a male patient with focal epilepsy and Glanzmann’s thrombasthenia who experienced Thrombophlebitis (TP) after oral administration of Carbamazepine (CBZ).
Methods: In an epileptic patient with malacia from intracerebral hemorrhage in left parietal and occipital lobes due to thrombasthenia, TP occurred following treatment of antiepileptic drug CBZ. Based on the dynamic changes of clinical manifestation and dosage of CBZ, in combination with the test results of D-Dimer, fibrinogen, prothrombin degradation products, and other laboratory tests, especially of Adenosine Diphosphate (ADP) and Arachidonic Acid (AA) evoked platelet aggregation tests, the etiology and pathophysiology of TP was explored.
Results: Six months after CBZ application with 200 mg bid, TP in the right lower extremity .. View More»
DOI:
10.4172/2161-1025.1000121