ISSN: 2167-7948
+44 1300 500008
Yasushi Noguchi
Japan
Research Article
The Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma is not an Aggressive Subtype of Papillary Carcinoma
Author(s): Hiroto Yamashita, Shiro Noguchi, Hiroshi Takahashi, Shin Watanabe, Shinya Uchino, Tsukasa Murakami, Hitoshi Noguchi, Yui Nishijima, Tomohiko Nakamura, Naoyuki Higaki, Masato Nakamoto, Yasushi Noguchi and Akiko Nakashima
Hiroto Yamashita, Shiro Noguchi, Hiroshi Takahashi, Shin Watanabe, Shinya Uchino, Tsukasa Murakami, Hitoshi Noguchi, Yui Nishijima, Tomohiko Nakamura, Naoyuki Higaki, Masato Nakamoto, Yasushi Noguchi and Akiko Nakashima
Background: The diffuse sclerosing variant of papillary thyroid carcinoma (DSV) is a rare subtype of papillary thyroid carcinoma (PTC), and the prognosis of patients with this variant is not yet fully understood. The aim of this study was to determine whether DSV is a poorer prognostic factor than non-DSV.
Methods: We reviewed the histologic slides of 12,664 primary PTC cases and divided them into DSV and non- DSV groups. Based on the results of the follow-up study and the age distribution of patients, we selected the data from 810 female patients and compared outcomes between patients with DSV and patients with non-DSV.
Results: Of all initial patients, 43 had DSV. Of these, 4 patients were deceased, and 39 were alive with a mean survival of 11.1 ± 9.7 years (mean ± SD) after surgery; the deceased patients.. View More»
DOI:
10.4172/2167-7948.1000163