ISSN: 2329-9509
+44 1478 350008
Yi-Hsun Yu
Musculoskeletal Research Center, Chang Gung Memorial Hospital,
People's Republic of China
Research Article
Demonstration of the Static Magnetic Fields Inability to Improve the Bone Mineral Density in an Osteoporotic Rat Model
Author(s): Yi-Hsun Yu and Tsung-Ting TsaiYi-Hsun Yu and Tsung-Ting Tsai
Objectives: Osteoporosis is a raising public health issue. There are several medications in the treatment of osteoporosis and osteoporotic-related fractures involving either enhancement of the osteogenesis or inhibition of the osteoclastogenestis. However, each medication has side effect. Therefore, we try to look for an alternative therapy for the treatment of osteoporosis, which increases bone mineral density without accompanying side effects.
Methods: In the current study, we used a Static Magnetic Field (SMF) to evaluate the hypothesis of improvement of the bone mineral density after an SMF exposure. In-vitro, we tested the capacities of osteogenesis and osteoclastogenesis on Mesenchymal Stem Cells (MSCs). In-vivo, we implanted a permanent magnet adjacent to the vertebrae in an osteoporotic rat model to examine the effects on the treatme.. View More»
DOI:
10.4172/2329-9509.1000218