ISSN: 2329-9096
+44 1300 500008
Yoshihiko Okudera
Japan
Research Article
Optimum Stimulation Frequency of High-Frequency Repetitive Transcranial
Magnetic Stimulation for Upper-Limb Function in Healthy Subjects
Author(s): Motoyuki Watanabe, Toshiki Matsunaga, Yoshihiko Okudera, Mineyoshi Sato, Kazutoshi Hatakeyama, Satoaki Chida, Yusuke Takahashi and Yoichi ShimadaMotoyuki Watanabe, Toshiki Matsunaga, Yoshihiko Okudera, Mineyoshi Sato, Kazutoshi Hatakeyama, Satoaki Chida, Yusuke Takahashi and Yoichi Shimada
Objective: Because rTMS requires the subject’s head to be immobilized and the subject to maintain the same posture throughout stimulation, stimulation of long duration may induce discomfort. If changing the stimulation parameters can allow the duration of rTMS to be shortened, physical discomfort may decrease. The purpose of this study was to identify the most beneficial stimulation parameters for high-frequency rTMS in terms of the effect on upper-limb function in healthy subjects. Materials and Methods: Forty right-handed healthy volunteers were divided into four groups: three real rTMS groups (5, 10, and 20 Hz rTMS) and one sham group. In the real rTMS groups, 600 impulses were applied at a frequency of 5, 10, or 20 Hz and an intensity of 90% of resting motor threshold. Performance on a peg-board task, tapping task, and grip strength were measured before stimulation, immediat.. View More»
DOI:
10.4172/2329-9096.1000310