Mycobacterial Diseases
Open Access

Yoshihiro Kobashi

Publications

• Research Article
  Clinical Evaluation of IP-10 and MIG for the Diagnosis of Active Tuberculosis Disease
  Author(s): Yoshihiro Kobashi, Keiji Mouri, Shigeki Kato and Mikio Oka Yoshihiro Kobashi, Keiji Mouri, Shigeki Kato and Mikio Oka
  
  Background: The aim of this study was to evaluate the clinical potential of IP-10 and MIG as biomarkers of tuberculosis (TB) infection adding a comparison with IGRAs (QFT and T-SPOT.TB). Materials and Methods: The subjects consisted of 52 patients with active TB disease and 86 patients with non-TB disease. We measured two IGRAs using peripheral blood (PB), and IP-10 and MIG using the supernatant from whole blood stimulated with MTB (Mycobacterium tuberculosis)-specific antigens. Results: In the patient group with active TB disease, while the positive response rates of QFT and T-SPOT.TB were 81% and 87%, that of IP-10 using the supernatant was 88% and that of MIG was 85%. In the patient group with non-TB disease, the positive response rate of QFT was 13%, and that of T-SPOT.TB was 14%, IP-10 using the supernatant wa.. View More»
  DOI: 10.4172/2161-1068.1000185

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