Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
Yuji Shiina
12-55 Wakaba-cho, Shinjo, Yamagata, Japan 996-0025
Japan
Research Article
Changes of Estradiol (E2) Concentration and Sex Hormone Binding Globulin (SHBG) Concentration in Serum during Controlled Ovarian Hyperstimulation (COH) in Pregnant and Non-pregnant Women
Author(s): Yuji Shiina
Yuji Shiina
Close correlation of Estradiol (E2) concentration and SHBG concentration in serum under the condition of Controlled Ovarian Hyperstimulation (COH) were investigated. E2 and SHBG coordinate each other but their secretion pattern was different. Serum E2 started to increase from D -4, became peak at D +1 then decreased rapidly next 2 days. Serum SHBG started to increase from D -1, reached peak at D +3 then kept high level during luteal phase.
Different situations of these hormones between pregnant and non-pregnant women under the condition of COH were also investigated. Though serum E2 and serum SHBG were not different at the time of hCG injection (D0) between the pregnant and the non-pregnant group, the ratio of these two was different. In the non-pregnant group SHBG/Estradiol (S/E ratio) was significantly higher (p<0.05) than pregnant group at the time of hCG injection (D0.. View More»
DOI:
10.4172/2161-0932.1000215