Journal of Clinical Toxicology
Open Access

Yu-Pei Wu

Publications

• Case Report
  Acute Liver Failure Induced by Sorafenib Combined with Diclofenac Sodium: A Case Report
  Author(s): Yue-Song Yin, Yu-Pei Wu, Xin-Na Deng, Li-Xiang Bai and Qing-Xia Li Yue-Song Yin, Yu-Pei Wu, Xin-Na Deng, Li-Xiang Bai and Qing-Xia Li
  
  Introduction: Drug-induced liver injury is one of the most common adverse drug reactions in clinical. Sorafenib is a widely used in hepatoma patients, while diclofenac sodium in patients suffering from cancer pain. Both of the two drugs showed mild and unfrequented liver damage. However, taking both drugs orally at the same time may cause severe liver function abnormity and there are few reports at present. Case report: We'll expatiate on an unusual case of a patient with kidney cancer who takes sorafenib and diclofenac sodium simultaneously and suffered from severe and acute liver failure about nearly two months. Conclusion: Sorafenib and diclofenac are likely to have some interactions. Clinically, the combination of the two should be carefully considered to reduce the potential risk of liver damage and avoid liver .. View More»
  DOI: 10.4172/2161-0495.1000407

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