Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Zahra Sayyed Bonakdar
West Indies
Research Article
Association of Helicobacter pylori Infection with Systemic Lupus Erythematosus
Author(s): Arefeh Ejtehadi, Rasoul Roghanian* and Zahra Sayyed Bonakdar
Arefeh Ejtehadi, Rasoul Roghanian* and Zahra Sayyed Bonakdar
Objective: Systemic Lupus Erythematosus (SLE) is an autoimmune disease of unknown etiology. However, a complex combination of host and environmental factors are believed to play a pivotal role. In the pathogenesis of SLE, several infectious agents have been held responsible such as Cytomegalovirus, Parvovirus B19, Epstein Barr virus and Retrovirus. There is a variable relationship between SLE and Helicobacter, which is different from that of lupus and other infections. The aim of this study was to investigate the association between Helicobacter pylori (H.pylori) infection and SLE development.
Method: In this study, 82 serum samples and 65 stool samples were collected from the SLE patients as well as the control group, respectively. An enzyme-linked immunosorbent assay (ELISA) was used to detect the presence of specif.. View More»
DOI:
10.4172/2155-9899.1000528