Medicinal & Aromatic Plants
Open Access

Zamilpa A

Publications

• Research Article
  Therapeutic Effectiveness of an Herbal Medicinal Product of Hibiscus sabdariffa in Hypertensive Patients: A 16 Week Controlled and Randomized Clinical Study
  Author(s): Herrera-Arellano A, Zamilpa A, Jiménez-Ferrer JE, Cruz-Hernández AM, Clemente-Catonga A, Herrera-Alvarez S and Tortoriello J Herrera-Arellano A, Zamilpa A, Jiménez-Ferrer JE, Cruz-Hernández AM, Clemente-Catonga A, Herrera-Alvarez S and Tortoriello J
  
  Background: The antihypertensive effectiveness of extracts from Hibiscus sabdariffa, has been reported in clinical studies of short term. This paper reports the therapeutic effectiveness, safety, and tolerability of an Herbal medicinal Product of Hibiscus sabdariffa administered during 16 weeks to hypertensive patients. Study design: Randomized, double-blind, controlled clinical trial. Patients: Adults with mild-to-moderate hypertension. Interventions: Experimental, capsules with H. sabdariffa extract (standardized in 100 mg of total anthocyanins); Control, capsules with Lisinopril (5 mg). Dosage: One capsule every 12 h for 16 weeks. Primary outcome: Therapeutic effectiveness (reduction ≥ 10 mmHg of baseline diastolic blood pressure); Tolerability (absence of intense adverse reactions); Safety (absence of pathol.. View More»
  DOI: 10.4172/2167-0412.1000265

  Abstract PDF

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