Endocrinology & Metabolic Syndrome
Open Access

Zehra Pınar Koç

Publications

• Research Article
  Transfection with Sodium Iodine Symporter Gene (NIS) and Future Applications with Radioiodine Treatment
  Author(s): Zehra Pinar Koc, Berfin Temelli, Leyla Kilic and F Selcuk SimsekZehra Pinar Koc, Berfin Temelli, Leyla Kilic and F Selcuk Simsek
  
  Human sodium iodine symporter gene (NIS) is the responsible factor for the effectiveness of radioiodine treatment in differentiated thyroid carcinoma. Previous studies in the literature have shown that loss of the NIS gene expression is the reason of ineffective treatment and dedifferentiation of the thyroid cancer. Definitely radioiodine treatment is the most effective cancer treatment method in the world. Probable applications of this treatment to the other types of tumors (like breast cancer, prostate cancer ect.) was the expected and wanted outcome of previous related studies which would be preferable to any kind of other treatments like chemo or radiation therapy. This has been achieved by transfection of cell lines with NIS gene by viruses. Additionally there have been these kinds of studies in the literature however none of these studies consist a stimulating factor like thyrot.. View More»
  DOI: 10.4172/2161-1017.1000139

  Abstract PDF

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